An Information Technology Framework for Predictive, by Leonard Berliner, Heinz U. Lemke

By Leonard Berliner, Heinz U. Lemke

This e-book explores how PPPM, medical perform, and uncomplicated study may be top served by means of info know-how (IT). A use-case was once built for hepatocellular carcinoma (HCC). the topic was once approached with 4 interrelated projects: (1) overview of scientific practices in terms of HCC; (2) suggest an IT procedure with regards to HCC, together with medical selection aid and examine wishes; (3) make sure how a scientific liver melanoma heart can give a contribution; and, (4) research the improvements and influence that the 1st 3 projects may have at the administration of HCC. An IT process for customized medication (ITS-PM) for HCC will give you the skill to spot and confirm the relative worth of the large variety of variables, together with medical review of the sufferer -- practical prestige, liver functionality, measure of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic point; tumor burden and person sufferer reaction; clinical and operative remedies and their outcomes.

Show description

Read Online or Download An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma PDF

Best technology books

Technology Matters: Questions to Live With

Know-how concerns, writes David Nye, since it is inseparable from being human. now we have used instruments for greater than 100,000 years, and their important objective has now not consistently been to supply must haves. humans excel at utilizing previous instruments to resolve new difficulties and at inventing new instruments for extra dependent options to outdated initiatives.

Introduction to a Future Way of Thought: On Marx and Heidegger

"Technologists purely swap the realm in a number of methods in generalized indifference; the purpose is to imagine the realm and interpret the adjustments in its unfathomability, to understand and adventure the adaptation binding being to the not anything. ’

Anticipating the age of planetary know-how Kostas Axelos, a Greek-French thinker, techniques the technological query during this ebook, first released in 1966, through connecting the idea of Karl Marx and Martin Heidegger. Marx famously declared that philosophers had in basic terms interpreted the area, however the aspect was once to alter it. Heidegger on his half under pressure that our sleek malaise used to be as a result forgetting of being, for which he inspiration technological questions have been critical. Following from his research of Marx as a philosopher of expertise, and foreseeing debates approximately globalization, Axelos acknowledges that know-how now determines the realm. delivering an creation to a couple of his significant subject matters, together with the play of the area, Axelos asks if planetary expertise calls for a brand new, a destiny method of suggestion which in itself is planetary. ”

Transforming Technology: A Critical Theory Revisited

Completely revised, this new version of severe conception of know-how rethinks the relationships among expertise, rationality, and democracy, arguing that the degradation of work - in addition to of many environmental, academic, and political platforms - is rooted within the social values that preside over technological improvement.

2012: Decoding the Countercultural Apocalypse

21 December 2012 was once believed to mark the tip of the 13th B'ak'tun cycle within the lengthy count number of the Mayan calendar. many of us believed this date to mark the top of the realm or, not less than, a shift to a brand new type of international recognition. studying how a lot of the phenomenon relies at the old list and what kind of is modern fiction, the e-book explores the panorama of the trendy apocalyptic mind's eye, the economics of the non secular market, the commodification of countercultural values, and the cult of famous person.

Additional info for An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma

Sample text

Oncogene 29:2309–2324 5. Perz JF, Armstrong GL, Farrington LA, Hutin YJ, Bell BP (2006) The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol 45:529–538 6. El-Serag HB, Rudolph KL (2007) Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132:2557–2576 7. Donato F, Boffetta P, Puoti M (1998) A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma.

D. Extraction is flexible and controllable by the end-user and researchers. e. Extraction may take in a variety of formats or representations—charts, tables, lists, images, graphs, and models. f. The DPM allows and facilitates simulations, prognosis, prediction, and therapy planning. One of the key functions of the DPM is to allow simulated evaluation of hypothetical, alternative therapies to predict and optimize patient outcomes, and to anticipate adverse effects of the proposed therapies. The DPM allows comparisons and compilations with other DPMs to collect Model-Based Medical Evidence, Population-Based Medical Evidence, and Disease-Based Medical Evidence.

Once the preliminary MEBN and PSM template have been established, the addition of patient records, images, and outcomes in the appropriate TIMMS Repositories will allow the creation of a functioning MEBN. It is our goal to utilize this IT approach to medical management to maximize the use of established medical information, to assist decision making, to advance our understanding of health and disease when there is incomplete medical knowledge, and to facilitate PPPM. References 1. Lemke HU, Berliner L (2010) Personalized medicine and model-guided therapy.

Download PDF sample

Rated 4.94 of 5 – based on 5 votes

Related posts