A History of Genetics by A.H. Sturtevant

By A.H. Sturtevant

Within the small Fly Room at Columbia collage, T.H. Morgan and his scholars, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, performed the paintings that laid the principles of contemporary, chromosomal genetics. the thrill of these instances, while the full box of genetics used to be being created, is captured during this e-book, written in 1965 by means of a type of current firstly. His account is likely one of the few authoritative, analytic works at the early heritage of genetics. This appealing reprint is observed by means of an internet site, http://www.esp.org/books/sturt/history/ supplying full-text models of the major papers mentioned within the publication, together with the world's first genetic map.

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During the period in question, a quite different approach to the study of heredity was developed by Francis Galton. Galton, who was a cousin of Darwin, had carried out an experiment to test the theory of pangenesis. He performed extensive blood transfusions between different strains of rabbits and found no effects on their descendants in either the first or the second generation. Darwin admitted that he would have expected effects but felt that his gemmules were not necessarily to be expected in the blood, since the theory was supposed to apply even to organisms without a circulatory system.

Here, then, in 1911, was the essence of the chromosome interpretation of the phenomena of inheritance. There followed a period of great activity— the usual consequence of a major scientific breakthrough. The next chapter will be concerned with this development. * One of the genes involved in the case described by Lock concerned date of flowering in peas and did not lead to clearly separable classes. While his data indicated linkage, they were not amenable to exact analysis. C HAPTER 7 –––––––––––––––––––––––––––––– T HE “F LY R OOM ” When Daniel Coit Gilman became the first president of Johns Hopkins University in 1875, he assembled a remarkable group of scholars to supervise the graduate work there.

When rose was crossed to pea, a new type, called “walnut,” appeared; this did not seem to be, structurally, a combination of rose and pea. The relations became clear when it was found that the F2 ratio is 9 walnut : 3 rose : 3 pea : 1 single (again by Bateson and Punnett)— for Mendel had already shown that this ratio meant that two independent pairs of genes were segregating. The occasional occurrences of cases in which the heterozygote is intermediate, that is, strict dominance is absent, was indicated by Correns in a footnote added to his 1900 paper in proof.

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